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Furthermore, we describe a fine tuning in gene expression, which permit this specie to maintain the two distinct subpopulations necessary to face changeable environmental conditions

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At the same time, bile acid signaling pathways, including the farnesoid X receptor (FXR)FGF15 and TGR5glucagon-like peptide-1(GLP-1) axes, are disrupted, further promoting hepatic lipid accumulation and immune dysregulation